hdac3 activity Search Results


94
Sino Biological recombinant gst hdac3
Recombinant Gst Hdac3, supplied by Sino Biological, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hdac3+activity/HDAC3%2C+Active/bio_rxiv__2024__08__06__606634-162-13-15
Average 94 stars, based on 1 article reviews
recombinant gst hdac3 - by Bioz Stars, 2026-10
94/100 stars
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94
Sino Biological vitro delactylation assay recombinant gst hdac3
Vitro Delactylation Assay Recombinant Gst Hdac3, supplied by Sino Biological, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hdac3+activity/HDAC3%2C+Active/pm41291745-97-1-7
Average 94 stars, based on 1 article reviews
vitro delactylation assay recombinant gst hdac3 - by Bioz Stars, 2026-10
94/100 stars
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90
SignalChem i e hdac3 ncor2
The reported <t>HDAC3-selective</t> inhibitors for the treatment of a range of diseases.
I E Hdac3 Ncor2, supplied by SignalChem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hdac3+activity/HDAC3%2FNCOR2%2C+Active/pmc05978667-140-7-20
Average 90 stars, based on 1 article reviews
i e hdac3 ncor2 - by Bioz Stars, 2026-10
90/100 stars
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N/A
CRISPR/Cas9 KO Plasmids consists of HDAC3-specific 20 nt guide RNA sequences derived from the GeCKO (v2) library. For CRISPR gene knockout, gRNA sequences direct the Cas9 protein to induce a site-specific double strand break (DSB)
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N/A
CRISPR/Cas9 KO Plasmids consists of HDAC3-specific 20 nt guide RNA sequences derived from the GeCKO (v2) library. For CRISPR gene knockout, gRNA sequences direct the Cas9 protein to induce a site-specific double strand break (DSB)
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N/A
Recombinant human HDAC3 (full length)/NCOR2 (237-489) complex was expressed by baculovirus in Sf9 insect cells using a C-terminal GST-tag for HDAC3 and N-terminal GST-tag for NCOR2.
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N/A
Suitable for high throughput screening of HDAC-8 inhibitors (100 assays)
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N/A
Hdac3 CRISPRa kit CRISPR gene activation of mouse histone deacetylase 3
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N/A
HDAC3 CRISPRa kit CRISPR gene activation of human histone deacetylase 3
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N/A
Full-length recombinant human HDAC3 was expressed by baculovirus in Sf9 insect cells using a C-terminal GST tag.HDAC3 or Histone deacetylase 3 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase
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N/A
Suitable for high throughput screening of HDAC-8 inhibitors (100 assays)
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Image Search Results


The reported HDAC3-selective inhibitors for the treatment of a range of diseases.

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: The discovery of novel HDAC3 inhibitors via virtual screening and in vitro bioassay

doi: 10.1080/14756366.2018.1437156

Figure Lengend Snippet: The reported HDAC3-selective inhibitors for the treatment of a range of diseases.

Article Snippet: All the full-length recombinant human GST-tagged HDACs, i.e. HDAC3/NCoR2 (residues 237-489), HDAC1, HDAC2, HDAC8, HDAC4 and HDAC6) were purchased from SignalChem (British Columbia, Canada).

Techniques:

The workflow for the discovery of novel HDAC3 inhibitors. The number refers to the amount of chemical entities that entered the next component of the workflow.

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: The discovery of novel HDAC3 inhibitors via virtual screening and in vitro bioassay

doi: 10.1080/14756366.2018.1437156

Figure Lengend Snippet: The workflow for the discovery of novel HDAC3 inhibitors. The number refers to the amount of chemical entities that entered the next component of the workflow.

Article Snippet: All the full-length recombinant human GST-tagged HDACs, i.e. HDAC3/NCoR2 (residues 237-489), HDAC1, HDAC2, HDAC8, HDAC4 and HDAC6) were purchased from SignalChem (British Columbia, Canada).

Techniques:

Eleven cherry-picked and purchased compounds, and their inhibitory activity on  HDAC3  in terms of inhibition rate (%) at 10 μM.

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: The discovery of novel HDAC3 inhibitors via virtual screening and in vitro bioassay

doi: 10.1080/14756366.2018.1437156

Figure Lengend Snippet: Eleven cherry-picked and purchased compounds, and their inhibitory activity on HDAC3 in terms of inhibition rate (%) at 10 μM.

Article Snippet: All the full-length recombinant human GST-tagged HDACs, i.e. HDAC3/NCoR2 (residues 237-489), HDAC1, HDAC2, HDAC8, HDAC4 and HDAC6) were purchased from SignalChem (British Columbia, Canada).

Techniques: Activity Assay, Inhibition, Positive Control

Inhibitory effects of the hit compound 2 and its derivatives from substructure search on  HDAC3.

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: The discovery of novel HDAC3 inhibitors via virtual screening and in vitro bioassay

doi: 10.1080/14756366.2018.1437156

Figure Lengend Snippet: Inhibitory effects of the hit compound 2 and its derivatives from substructure search on HDAC3.

Article Snippet: All the full-length recombinant human GST-tagged HDACs, i.e. HDAC3/NCoR2 (residues 237-489), HDAC1, HDAC2, HDAC8, HDAC4 and HDAC6) were purchased from SignalChem (British Columbia, Canada).

Techniques:

The modes of compound 2 (A), 2–1 (B) and 2–2 (C) bound to HDAC3, predicted by FRED. Colour codes: light blue, HDAC3; green, hit compounds; blue sphere, zinc ion.

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: The discovery of novel HDAC3 inhibitors via virtual screening and in vitro bioassay

doi: 10.1080/14756366.2018.1437156

Figure Lengend Snippet: The modes of compound 2 (A), 2–1 (B) and 2–2 (C) bound to HDAC3, predicted by FRED. Colour codes: light blue, HDAC3; green, hit compounds; blue sphere, zinc ion.

Article Snippet: All the full-length recombinant human GST-tagged HDACs, i.e. HDAC3/NCoR2 (residues 237-489), HDAC1, HDAC2, HDAC8, HDAC4 and HDAC6) were purchased from SignalChem (British Columbia, Canada).

Techniques:

Activity profiling of three hit compounds, i.e. 2 , 2–1 and 2–2 against a panel of HDAC isoforms.

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: The discovery of novel HDAC3 inhibitors via virtual screening and in vitro bioassay

doi: 10.1080/14756366.2018.1437156

Figure Lengend Snippet: Activity profiling of three hit compounds, i.e. 2 , 2–1 and 2–2 against a panel of HDAC isoforms.

Article Snippet: All the full-length recombinant human GST-tagged HDACs, i.e. HDAC3/NCoR2 (residues 237-489), HDAC1, HDAC2, HDAC8, HDAC4 and HDAC6) were purchased from SignalChem (British Columbia, Canada).

Techniques: Activity Assay

Selectivity index (SI) of three  HDAC3  inhibitors over other HDAC isoforms.

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: The discovery of novel HDAC3 inhibitors via virtual screening and in vitro bioassay

doi: 10.1080/14756366.2018.1437156

Figure Lengend Snippet: Selectivity index (SI) of three HDAC3 inhibitors over other HDAC isoforms.

Article Snippet: All the full-length recombinant human GST-tagged HDACs, i.e. HDAC3/NCoR2 (residues 237-489), HDAC1, HDAC2, HDAC8, HDAC4 and HDAC6) were purchased from SignalChem (British Columbia, Canada).

Techniques: